Abstract
Staphylococcus aureus is a notorious foodborne pathogen since it has ability to produce variety of toxins including heat-stable enterotoxin, form biofilm, and acquire resistance to antibiotics. Biocontrol of foodborne pathogens by lytic bacteriophages garners increasing interest from both researchers and food industry. In the present study, 29 phages against S. aureus were successfully isolated from chicken, pork, and fish. Characterization of the isolates revealed that phage SA46-CTH2 belonging to Podoviridae family had a number of features suitable for food industry applications such as wide host range, short latent period, large burst size, high stress tolerance, and a genome free of virulence genes. Furthermore, phage SA46-CTH2 alone or in combination with nisin exhibited great efficacy in reducing planktonic and biofilm cells of S. aureus at various conditions tested. The combination of phage SA46-CTH2 and nisin was also found to be able to inhibit the regrowth of S. aureus at both 37 and 24 °C.
Hoang Minh Duc
FVM- Vietnam National University of Agriculture
Keywords: Bacteriophages, S. aureus, Biofilm, Antibiotic Resistance Link
I like it when people get together and share thoughts. Great blog, keep it up!
Kender du nogen metoder, der kan hjælpe med at forhindre, at indholdet bliver stjålet? Det ville jeg sætte stor pris på.
buď vytvořil sám, nebo zadal externí firmě, ale vypadá to.